Outreach + Highlights
The AGP laboratory conducts research on the diversity and biological evolution of human populations, with the main objective of reconstructing the history of world settlement since the origin of Homo sapiens.
Past human expansions shaped the spatial pattern of Neanderthal ancestry
The worldwide expansion of modern humans (Homo sapiens) started before the extinction of Neanderthals (Homo neanderthalensis). This study shows that inferences about past human population dynamics can be made from the spatiotemporal variation in archaic introgression.
Biology 23
16-17th February 2023 at Sciences II, University of Geneva.
Biology 23 is the largest conference of organismic biology in Switzerland and aims to provide a platform for exchange between students, researchers and professors across scientific institutions, research groups and topic areas.
Population designations in biomedical research: Limitations and perspectives
In biomedical research, population differences are of central interest. Variations in the frequency and severity of diseases and in treatment effects among human subpopulation groups are common in many medical conditions.
Ancient mitochondrial diversity in Neolithic Greece and along the Danubian expansion axis
This study investigates mitochondrial diversity in Neolithic Greece and its relation to hunter-gatherers and farmers who populated the Danubian Neolithic expansion axis.
Hommage à Pierre Moeschler
Pierre Moeschler, qui vient de nous quitter, a largement contribué à donner à l’Ecologie générale et humaine, la place qui lui revient dans la société et dans les universités européennes aujourd’hui, à Genève en particulier.
« L'autre n'est qu'autre »
Symposium sur la diversité humaine à l'occasion du départ à la retraite du Dr Ninian Hubert van Blijenburgh.
Rencontre avec Alicia Sanchez-Mazas, grande spécialiste de lʹévolution du système immunitaire
Une heure pour faire connaissance avec cette spécialiste de lʹévolution humaine et plus particulièrement de lʹévolution génétique de notre système immunitaire.
Spatially explicit paleogenomic simulations support cohabitation with limited admixture between Bronze Age Central European populations
Spatially explicit simulations of population dynamics combined with palaeogenomic data support the cohabitation of pastoralist and agriculturalist populations in Central Europe during the Bronze Age, with limited gene flow between them and a demographic decline after their initial contact.
Binding affinities of 438 HLA proteins to complete proteomes of seven pandemic viruses and distributions of strongest and weakest HLA peptide binders in populations worldwide
The main function of HLA class I molecules is to present pathogen-derived peptides to cytotoxic T lymphocytes. This function is assumed to drive the maintenance of an extraordinary amount of polymorphism at each HLA locus, providing an immune advantage to heterozygote individuals capable to present larger repertories of peptides than homozygotes.
The wings of a “genetic bird” protect us against viruses
UNIGE researchers have demonstrated that every population can protect itself against a broad range of viruses thanks to the two most diverse HLA immune genes in humans.